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Quantitative Literary Analysis of Aphra Behn’’s Works

為了解決Compared with的問題，作者Runge, Laura L. 這樣論述：

Aphra Behn (1640-1689), prolific and popular playwright, poet, novelist, and translator, has a fascinating and extensive corpus of literature that plays a key role in literary history. The book offers an analysis of all of Behn’s literary output. It examines the author’s use of words in terms of

frequencies and distributions, and stacks the oeuvre in order to read Behn’s word usage synchronically. This experimental analysis of Behn’s literary corpus aims to provide a statistical overview of Behn’s writing and a study of her works according to the logic of the concordance. The analysis demon

strates the interpretive potential of digital corpus work, and it provides a fascinating reading of synchronic patterns in Behn’s writing. The book aims to augment the practice of close-reading by facilitating the rapid moves from full corpus to unique subsets, individual texts, and specific passage

s. It facilitates the connections among works that share verbal structures that would otherwise not register in diachronic reading. Each chapter focuses on one type of writing: poetry, drama, and prose. The chapters begin with an overview of the documents that make up the corpus for the genre (e.g.

the 80 published poems attributed to Behn in her lifetime; 18 plays and 12 prose works). A section on statistical commonplaces follows (length of texts, vocabulary density, and most frequent words). Interesting textual examples are explored in more detail for provocative close readings. The statisti

cs then are contextualized with the general language reference corpus for a discussion of keywords. Each chapter features a unique comparative study that illustrates Behn in a specific context. Each chapter analyzes a specific genre and comparative statistical experiments within the genre. The concl

usion compares all three genres to provide a study of Aphra Behn’s oeuvre as a whole. The discussion is focused through the lens of Behn’s most remarkable words. The keywords for her oeuvre as compared to the literary works in the general language reference (fifteen texts) when the proper names and

stage directions are removed to provide an index of Behn’s characteristic themes and qualities: oh, young, lover, love, marry, charming, heart, gay, soft, goes. Each of these words opens a window on her corpus as a whole. A unique case study of a significant author using new literary methodologies,

this book provides an appealing snapshot of Behn’s whole career informed by deep knowledge of the Restoration era and developments in digital humanities and cultural analytics.

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An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Compared with的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

Surgical Techniques for Asian Rhinoplasty: A Practical Reference

為了解決Compared with的問題，作者Kim, Jae-Hoon,Park, Sung-Wan 這樣論述：

This practical book describes in detail surgical methods that yield excellent results when performing rhinoplasty in Asian patients. The coverage encompasses the full range of frequently encountered nasal deformities and the procedures employed in their correction. Precise descriptions of surgical t

echniques are complemented by a wealth of pre-, intra-, and postoperative illustrations as well as videos documenting actual operations. Attention is drawn to surgical pearls and pitfalls, and full guidance is also provided on patient preparation, anesthesia, and postoperative management. Rhinoplast

y is a challenging procedure, and surgeons who treat Asian patients must take into account the fact that, compared with Caucasians, they have smaller noses, weaker cartilage, and thicker skin. Moreover, cultural differences and variations in aesthetic standards need to be respected. The book clearly

explains the nasal anatomy for Asian rhinoplasty and its implications for surgical technique. It will serve as an ideal, easy-to-use reference for all surgeons who perform rhinoplasty in Asians, regardless of their level of expertise. Jae-Hoon Kim, MD, PhDApril 31 Plastic Surgery Clinic, Seoul, S

outh Korea

系統移轉關鍵因素之實務研究

為了解決Compared with的問題，作者陳慧姍 這樣論述：

隨著時代變遷與新業務的多樣化需求，一個行之己久的系統，除了穩定運作之外，系統快速變更的能力也是必需的，面對業務需求的增加及新技術發展，系統移轉開發升級是必然面對的課題，系統移轉前有足夠的溝通及明確的專案範圍定義，可讓系統移轉開發達到事半功倍的效果。本研究目的在針對系統移轉實務開發過程、相關文獻及專案管理知識指南 (PMBOK Guide, A Guide to the Project Management Body of Knowledge)，進行探討系統移轉關鍵指標因素及程式開發者規劃及應對，研究係採用專家訪談問卷並佐層級分析法研究方法分析推論其結果，達成研究結論，共計發出九份專家訪談問卷

，並回收九份，研究歸納結果顯示「系統移轉」關鍵要素計算出的權重比例前三項分別為「組織政策」、「專案目標」及「系統分析」。