Detected的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列包括價格和評價等資訊懶人包

Human Heartbeat Detected

為了解決Detected的問題，作者Clammer, Chelsey 這樣論述：

Human Heartbeat Detected is a collection of essays that explores how we are wonderfully and terrifyingly human. Hitting on themes such as trauma, emotional abuse, marriage, mental illness, and grief, these essays delve into how humans are simultaneously beautiful and terrible to one another. Thou

gh regardless of how we might make each other shatter, our hearts continue beating--even when we might not want them to--and we wade through the wreckage of our lives to find ways to survive. With exquisite language and captivating storytelling, the essays in Human Heartbeat Detected face what it me

ans to be human.

Detected進入發燒排行的影片

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Detected的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

Boat Troop

為了解決Detected的問題，作者Howard, Johnny 這樣論述：

Within two weeks of the Argentine invasion of the Falkland Islands, four men of Boat Troop, B Squadron, 22 SAS, are on the islands too. It is the mission of these four men to gather vital intelligence without being detected by Argentine patrols. The rest of B Squadron are tasked with a suicide mi

ssion-an attack on the Argentine airbase in the mainland. In charge is a man unafraid to risk the lives of his men in search of greater personal glory.

汽車多雷達系統之擴展目標追蹤

為了解決Detected的問題，作者葉冠華 這樣論述：

本論文主要考慮在道路環境中之擴展目標追蹤問題。在擴展目標追蹤中，必須估計運動學及形狀兩種參數。在道路上的目標不會是任意形狀的，通常有數個特定形狀作為候選。為了提高追蹤效能，我們首先提出將形狀估計問題轉換為形狀偵測的問題。計算候選形狀的似然函數，並使用最大似然 (maximum likelihood, ML) 原理進行偵測。一旦偵測到形狀，接著再次使用 ML來估計目標位置，並將結果與追蹤濾波器的輸出相結合。使用上述方法，我們進一步提出了兩種多雷達擴展目標追蹤方法，分散式和集中式方法。由模擬結果所示，所提出的方法明顯優於傳統的擴展目標追蹤方法。