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Ore Genesis and Deposit Model: The Mianning-Dechang Ree Belt in Western Sichuan Province, China

為了解決Fluid的問題，作者Xie, Yuling,Hou, Zengqian,Tian, Shihong 這樣論述：

Yuling Xie is an experienced University-based economic geologist with more than 25 years of teaching, research and field practice. Her core skills include mineral deposit genesis, structural geology and field studies, and applied geochemistry and mineralogy. She has gained international reputation i

n the field of REE deposit, fluid inclusion, and specialises in the integration of fluid inclusion studies with mineral deposit models. She has worked on a range of mineral deposit types including: carboniatite-hosed REE deposits, porphyry copper systems, lode-gold deposits, epithermal silver and po

lymetallic systems, hydrothermal zinc-lead deposits, andcopper-iron skarns. Research outcomes from her research have been presented at various national and international conferences and published in journals in both Chinese and English.

Fluid進入發燒排行的影片

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Fluid的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

Optimal Transport Networks in Nature

為了解決Fluid的問題，作者Kizilova, Natalya 這樣論述：

This unique book presents a broad range of data on geometry and topology of long-distance liquid transport networks in nature including circulatory and respiratory systems of mammals, trophic fluid transport systems of animals, and conducting systems of higher plants. It is the very first book wh

ere evidence of the common design principles and optimal properties of the transportation networks of vascular plants and animals is provided.The book also provides a comprehensive comparative study of the recent measurement results and data analysis, including unique data obtained by the author to

conduct systems of plant leaves of different shapes, sizes, venation types and evolutionary ages. It was shown that the mathematical solutions of the optimization problem for the animal and plant conducting systems lead to the same design principles, despite different physical conditions of the flui

d transport.

三相電磁噴流之研究

為了解決Fluid的問題，作者鄭力瑋 這樣論述：

摘要電磁噴流是一種運用磁流體力學(Magnetohydrodynamics, MHD)之概念，當給予電極板電能與固定磁場時，便可產生勞倫茲力，藉此推動導電流體。其優點在於致動原理簡易，且不需要依靠複雜的機械結構，便可實現推送之效果。常見的應用在微尺度之微動幫浦與大型船體無槳式推進器上，以往許多研究都著重在電場與磁場之設計與幾何構型的最佳化，而本研究透過實驗探討在電磁噴流中，電極板附帶產生電化學反應而生成氣泡所構成之多相噴流場。並藉由染劑與氣泡之方式發展一流場可視化之方法。本研究透過計算染劑之汙染面積並與數值模擬結果進行比較，發現在低電流時之預測流量結果較為相近。並定義一無因次參數為勞倫茲力雷

諾數(Re_L)，用以描述電磁噴流之流場型態，實驗結果透過定性觀察當勞倫茲力雷諾數(Re_L)大於1600時，噴流型態會發展成紊流的型式。透過無因次分析結果也顯示其噴流擴散角(θ)與氣泡佔比(Ag)有隨Re_L數增加而有上升之趨勢，且在Re_L數大於1600後，因流場型態轉變，擴散角與氣泡佔比也有明顯上升之現象。在最後討論使用鋁電極板對於電磁噴流之影響。