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多功能環保量子點作為靶向雙成像和光動力癌症治療平台

為了解決Qiao ptt的問題，作者諾菲 這樣論述：

Recommendation letter iiAbstract in chinese iiiAbstract in english vAcknowledgments viiContents viiiList of figures xiiList of tables xviiList of abbreviation ixChapter 1. Introduction 11.1 General introduction 21.2 Objective of study 61.3 Structure of the dissert

ation 6Chapter 2. Literature review 82.1 Nanoparticles 92.2 Semiconductor quantum dots 102.3 The quantum confinement, optical properties, and core/shell structure of QDs 122.4 Synthesis of QDs 192.4.1 Nucleation and growth 212.4.2 Hot injection method 252.4.3 Heat-up method

282.4.4 Solvothermal approach 312.4.5 Hydrothermal approach 332.4.6 Microwave irradiation approach 352.5. Folate receptor targeting agents 382.6 QDs biomedical applications 422.6.1 Optical imaging 422.6.2 Magnetic resonance imaging (MRI) 442.6.3 Drug delivery 462.6.4 Photo

‑dynamic therapy (PDT) and Photo‑thermal (PTT) therapy 59Chapter 3. Manganese-doped green tea-derived carbon quantum dots as a targeted dual imaging and photodynamic therapy platform 483.1 Introduction 523.2 Experimental methods 533.2.1 Materials 553.2.2 Synthesis of Mn-CQD 563.2.

3 Preparation of Mn-CQDs@FA/Ce6 563.2.4 Characterization 573.2.5 Cell structure and viability evaluation 583.2.6 In vitro photodynamic cancer cells’ ablation 593.2.7 Cell imaging 603.3 Results 603.3.1 Synthesis of Mn-CQDs 603.3.2 Preparation of Mn-CQDs@FA/Ce6 643.3.3 Photolu

minescence characteristics and ROS generation of Mn-CQDs@FA/Ce6 conjugates 663.3.4 Mn-CQDs as MRI contrast agents 693.3.5 In vitro cellular uptake and therapeutic effect 723.4 Discussion 753.5 Summary 77Chapter 4. Multifunctional MnCuInSe/ZnS quantum dots for bioimaging and photodyna

mic therapy 794.1 Introduction 804.2 Experimental methods 834.2.1 Materials 834.2.2 Synthesis of the CuInS, CuInSe, MnCuInSe core and CuInS/ZnS, CuInSe/ZnS and MnCuInSe/ZnS core/shell carbon quantum dots 844.2.3 Characterization 854.2.4 Optical and photoluminescence properties of

MnCuInSe/ZnS assay 854.2.5 Photoactivity assessment of MnCuInSe/ZnS 864.2.6 In Vitro MR 864.2.7 Cell culture and in vitro cytotoxicity evaluation 874.2.8 Cell imaging 884.3. Results and discussion 884.3.1. Synthesis and characterization of MnCuInSe/ZnS 884.3.2 Optical and photol

uminescence properties of MnCuInSe/ZnS 904.3.3 Stability of MnCuInSe/ZnS QDs colloidal solution 944.3.4 ROS generation of MnCuInSe/ZnS 974.3.5 Magnetic resonance imaging 984.3.6 In vitro cellular uptake and therapeutic effect 1014.3.7 Confocal imaging 1024.4. Summary 105Chapte

r 5. Conclusions 1065.1 Conclusions 1075.2 Future outlooks 109References 110Appendix 134

教導國小五年級學童檢查及修改病句策略對其校正病句成效之行動研究

為了解決Qiao ptt的問題，作者何淑惠 這樣論述：

本研究採行動研究法，探究教導學生檢查及修改病句策略對其校正病句的教學歷程、成效及學生的看法。研究者以高雄市某國小五年級30位學生為研究對象，實施9週共18節課的教學。教學前，先對學生實施前測以評估該班學生的先備知識。教學時，採用三階段的課程（1.教導認識詞類、句子及句子的六大成分 2.教導檢查策略 3.教導檢查及修改病句）搭配鷹架四步驟的教學（1.教師示範 2.小組討論 3.作業練習 4.教師統整）。課程結束時，利用後測及教學後回饋表以了解教學後的成效。資料經過分析後得到以下研究結論：一、運用檢查及修改病句策略於國小五年級學童校正病句教學之歷程明確具有推廣價值（一）校正病句課程及教學架構的設

計有助學生能力的堆疊。（二）解題四步驟有助學生順利解題。（三）鷹架四步驟中的合作學習能發揮學習效果。二、教導學童運用檢查及修改病句策略提升校正病句的成效顯著三、學童對於運用檢查及修改病句策略於校正病句課程持正面看法（一）學童能理解語法專有名詞。（二）學童認為學習校正病句課程並不困難。（三）學童會自動使用斷詞法及簡縮法這兩種策略來辨識病句。（四）學童認為合作學習對本課程有很大的助益。（五）學童高度接受本教學課程。研究者根據研究結果提出教學和未來相關研究的建議。