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From the Stage to the Studio: How Fine Musicians Become Great Teachers

為了解決Stage Design的問題，作者Watkins, Cornelia,Scott, Laurie 這樣論述：

An expanded, updated, and improved second edition of an essential book for aspiring teacher-musicians.Few musicians depend upon performing for their sole source of income. No matter one’s level of technical accomplishment or expressive ability, musicians who distinguish themselves as both skilled

performers and teachers will have significant career advantages. Authors Cornelia Watkins and Laurie Scott draw on their extensive experience in both pedagogy and performance to provide the structure, information, and tools musicians need to nurture successful students and establish rewarding caree

rs. This second edition promotes diversity and equity in all aspects of music teaching and performance, addresses the pros and cons of virtual instruction, and offers less-frequently considered financial ideas for the self-employed. All are enhanced by the new reader-friendly design, which includes

space for readers to log learning reflections. Whether building career possibilities as a music school student or adding teaching to an extensive performance résumé, From the Stage to the Studio offers anyvocalist, instrumentalist, or conductor the guidance and support for a fulfilling career as an

artist-teacher.

Stage Design進入發燒排行的影片

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Stage Design的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

The Sensory Studies Manifesto: Tracking the Sensorial Revolution in the Arts and Human Sciences

為了解決Stage Design的問題，作者 這樣論述：

The senses are made, not given. This revolutionary realization has come as of late to inform research across the social sciences and humanities, and is currently inspiring groundbreaking experimentation in the world of art and design, where the focus is now on mixing and manipulating the senses.T

he Sensory Studies Manifesto tracks these transformations and opens multiple lines of investigation into the diverse ways in which human beings sense and make sense of the world. This unique volume treats the human sensorium as a dynamic whole, which is best approached from historical, anthropologic

al, geographic, and sociological perspectives. In doing so, it has altered our understanding of sense perception by directing attention to the sociality of sensation and the cultural mediation of sense experience and expression.David Howes challenges the assumptions of mainstream Western psychology

by foregrounding the agency, interactivity, creativity, and wisdom of the senses as shaped by culture. The Sensory Studies Manifesto sets the stage for a radical reorientation of research in the human sciences and artistic practice.

設計趨勢預測應用於設計思考流程之研究

為了解決Stage Design的問題，作者林貞瑜 這樣論述：

台灣近年愈來愈重視設計產業，政府提倡將設計作爲企業的目標策略與核心，不過目前許多政策仍在規劃階段，只有少數成功的大型企業，早已開始進行設計趨勢相關的研究工作，因此本研究動機為瞭解企業執行設計趨勢的目的與過程，以及對設計師的影響。本研究採用質性研究中的半結構式訪談，以台灣本土大型科技企業之設計中心作為本研究之個案，透過研究目的：一、瞭解企業內部如何進行設計趨勢預測與彙整。二、企業內之設計師如何應用設計趨勢進行設計思考與發想。三、設計趨勢對於企業內的設計師的影響為何。以及文獻探討的歸納，聚焦於企業中執行設計趨勢預測與設計思考之流程及應用，以及企業內之設計師認為趨勢預測之於個人或公司之影響，訪綱分

為四大類，共26道題目，分別訪談八位參與過設計趨勢研究之設計師，從中瞭解設計趨勢的重要性。本研究依照企業內部設計師們所提供的經驗與建議，研究者根據訪談結果提出下列點結論：1、企業內之設計中心執行趨勢，會綜合多種不同形式的團體預測方法使用，每年無固定使用之方法，會依據人員、目標的不同去做調整，訂定趨勢結論。；2、企業全體人員可從宏觀趨勢抓取機會點，在成立新專案時導入，而設計人員可從設計趨勢抓取應用面，在設計發想時導入使用，或是設計提案時導入設計理念中。；3、設計趨勢對於設計師而言，是一個與時俱進的工具書，使設計作品在產業界的壽命更加長遠。4.趨勢研究結果不需要強制在設計中心內部去做驗證，可以從市

場回饋中得到答案。