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Embedded Dielectrics for Electronic Packaging

為了解決matrix的問題，作者Yu, Shuhui/ Sun, Rong/ Wong, Ching Ping 這樣論述：

This book provides an overview of nanocomposite materials that can be used as embedded dielectric layer in high-density electronic packaging, for decoupling, filtering, energy storage or electrostatic discharge suppressing, etc. Some fundamental models used to analyze or predict the dielectric be

havior of ceramic/polymer, conductor/polymer, and semiconductor/polymer composites are reviewed. This book also introduces design and synthesis of some novel hybrid filler particles, as well as graft modification on the polymer matrix to improve dielectric performance.

matrix進入發燒排行的影片

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決matrix的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

Gulf Gothic: Mexico, the U.S. South and La Llorona’’s Undead Voices

為了解決matrix的問題，作者Cartwright, Keith,Flores-Silva, Dolores 這樣論述：

Gulf Gothic moves through deep time across languages and borders, presenting haunted, secret-laden narratives that emerge from the gulfs between people all along the Gulf of Mexico and on both sides of the Rio Grande. Collaborating in an interdisciplinary manner, literary and cultural critics Dol

ores Flores-Silva and Keith Cartwright chart the Gulf as a unified region and ground zero of North American (and global) transculturation.The Gulf of Mexico has been inadequately appreciated as the dynamic transnational region that it is (taking in the Gulf states of Mexico and the U.S., as well as

western Cuba), a cultural matrix that nourished the spread of maize agriculture and the rise of a two-thousand-year-old literary historical tradition that has responded to traumas of colonial conquest and plantation slavery. In this study, the Gulf signifies metaphorically and symbolically--as undea

d space of contacts and supposed impasses between peoples--as well as topographically. Its gothic modalities carry an urgent charge that demands to be addressed in holistic formGulf Gothic addresses modes of representing all that is blocked from free movement and aspiration. Here, the figure of La L

lorona haunts boundary waters and shorelines, voicing much that has been occulted by colonial power and national narrative. La Llorona’s Indigenous prototypes, plantation/hacienda atmospherics, and heated storm patterns show up repeatedly in variations of an originary undeadness unconstrained by att

empted quarantines and border walls. The authors turn to cinematic horror and the double gaze of ancient Maya texts, to folk-fable and legal documents and popular song, as well as to works by Gloria Anzaldúa, Sandra Cisneros, Leslie Marmon Silko, Joy Harjo, LeAnne Howe, Kate Chopin, James Weldon Joh

nson, William Faulkner, Carlos Fuentes, Vicente Riva Palacio, Jesmyn Ward, and Fernanda Melchor, to attend to forces unbound by traditional gothic modalities and their foundational gulfs.

運用商業管理TRIZ 改善國軍人才招募

為了解決matrix的問題，作者王銘仁 這樣論述：

國軍的招募員自從2017年開始施行全募兵制後，就扮演了相當重要的角色，需要對青年學子及社會大眾解說國軍的生態與面貌，找尋適合的人才加入國軍，但不是每個人都能接受軍職這項工作，間接的造成了某些軍種招生不易的狀況發生，也因此上級長官開始給予壓力，促使招募人員開始以避重就輕的方試招攬人才，使得社會大眾對國軍開始產生誤解與矛盾，本研究透過設計訪談的方式得出結果來界定問題，接著利用商業管理TRIZ理論中的觀點圖，找出招募工作需要改善的地方與問題，再來透過根源矛盾分析(RCA+)，找到問題與原因的矛盾之處，最後利用矛盾矩陣與四十個發明原理產生創新的招募員管理方案，並透過排列出點子優先順序的方式，選出適合

招募員管理的方案，以產出創新方法與建議解決方案。最終產生五項改善方案，其中之最佳方案為「把原先需要多天完成的行程合理安排合併減少天數」為最理想方案，因其所需準備時間最短，而且無論在招募組組長接受度或資深招募員方面皆能達到最高成效為最佳方案，可以可在短時間內減輕招募員眼前困擾的方法；長期則以成立獨立招募單位管理招募更能徹底解決相關問題。