走在汽車革命的路上論文書籍站
Epithelial cells的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列包括價格和評價等資訊懶人包
Epithelial cells的問題，我們搜遍了碩博士論文和台灣出版的書籍，推薦寫的 Stem Cells in Veterinary Science 和的 Deferring Development: Setting Aside Cells for Future Use in Development and Evolution都 可以從中找到所需的評價。
另外網站Epithelial Tissue is Key to Healthy Gut, Skin and Claw Integrity也說明：To maintain a protective layer and cellular structure, epithelial cells contain a cytoskeleton matrix composed of keratin filaments or tightly-wrapped protein ...
這兩本書分別來自 和所出版 。
國立陽明交通大學 分子醫學與生物工程研究所 趙啟宏所指導 王慶弘的 探討CPT1C在類基底型乳癌中調控上皮-間質轉型及腫瘤幹細胞特性所扮演的角色 （2021），提出Epithelial cells關鍵因素是什麼，來自於脂肪酸氧化、CPT1C、類基底型乳癌、上皮-間質細胞轉型、腫瘤幹細胞特性。
而第二篇論文國防醫學院 醫學科學研究所 余慕賢、張正昌所指導 蘇國銘的 透過基於基因本體之整合性分析識別卵巢上皮性腫瘤發病機轉的失調基因功能體 （2021），提出因為有 漿液性上皮性卵巢癌、卵巢清亮細胞癌、邊緣性卵巢腫瘤、基因本體、機器學習、整合性分析、補體系統、SRC基因、芳烴受體結合路徑、上皮細胞間質轉化的重點而找出了 Epithelial cells的解答。
最後網站3D Shape of Epithelial Cells on Curved Substrates則補充：Building a physical framework to account for the shape of cells in epithelia is thus an important challenge to understand various normal and ...
Stem Cells in Veterinary Science
為了解決Epithelial cells 的問題，作者 這樣論述：
Part 1: Overview And Introduction.- 1 Overview of Stem Cells and Their Applications in Veterinary Medicine.- 2 Introduction to Mammary Gland and its Cell Types.- 3 Mammary Stem Cells: How Much Do We Know?.- 4 Methods of Identification and Characterization of Stem Cells.- 5 Potential of Stem Cell
Therapy to Combat Mastitis in Dairy Animals.- PART 2: STEM CELLS AND VETERINARY RESEARCH.- 6 Fatty Liver Disease and Utility of Stem Cells in Developing the Disease Model.- 7 Mammary Epithelial Cells: A Potential Cellular Model to Understand the Impact of Heat Stress on Mammary Gland and Milk Produc
tion in Dairy Animals.- 8 Milk and Milk-Derived Stem Cells.- 9 Cryopreservation of Testicular Stem Cells and its Application in Veterinary Science.- 10 Testicular Stem Cell Niche.- 11 Proteomics of Mammary Cell Lines and Mammary Stem Cells.- PART 3: THERAPEUTIC APPLICATIONS.- 12 Advancing Quantitati
ve Stem Cell Dosing for Veterinary Stem Cell Medicine.-13 Mesenchymal Stem Cells: a novel therapy for the treatment of Bovine Mastitis.- 14 Therapeutic Applications of Mesenchymal Stem Cells in Canine Diseases.- 15 Biomaterials and Scaffolds in Stem Cell Therapy.- 16 Prospects of Mesenchymal Stem Ce
ll Secretome in Veterinary Regenerative Therapy.- 17 Reprogramming and Induced pluripotent stem cells in porcine.- 18 CRISPR/Cas System and Stem Cell Editing: Prospects and Possibilities in Veterinary Sciences.- PART 4: ISSUES AND PERSPECTIVES.- 19 Identification of Species-Specific Stem Cells and C
hallenges.- 20 Regulations of Animal Cell-Based Drugs in Veterinary Regenerative Medicine.
探討CPT1C在類基底型乳癌中調控上皮-間質轉型及腫瘤幹細胞特性所扮演的角色
為了解決Epithelial cells 的問題，作者王慶弘 這樣論述：
代謝途徑重整是腫瘤的重要特徵之一，腫瘤細胞可藉由調控自身的代謝偏好而有利其在代謝壓力的情況下存活，並維持高速增生。有研究更進一步指出乳癌細胞傾向於透過調控脂肪酸氧化代謝的效率限制酶CPT1C來增加脂肪酸氧化的活性，進而促進細胞增生，甚至維持腫瘤幹細胞特性及產生抗藥性。因此，本研究旨在釐清類基底型乳癌是否透過調節CPT1C影響細胞脂肪酸氧化代謝的活性，進而誘發上皮-間質細胞轉型及腫瘤幹細胞特性。我們的先導結果指出，透過TCGA數據資料庫分析，CPT1C表現量在類基底型乳癌患者中高於其他乳癌類型，並在具有淋巴結轉移或遠端轉移的患者中具有較高的表現量;而在類基底型乳癌患者中，擁有較高CPT1C表現
量的族群同時存活率也較差。此外，在類基底型乳癌患者中，相較於其他CPT1同功酶(CPT1A、CPT1B)， 唯有CPT1C的表現量和存活率呈現負相關。接著，正常類基底型人類乳腺上皮細胞中過度表現CPT1C會增加脂肪酸氧化代謝活性，同時也誘導上皮-間質細胞轉型、細胞遷移、侵襲，並且提升腫瘤幹細胞特性；反之，利用微小干擾RNA抑制類基底型乳癌細胞株的CPT1C表現則可降低腫瘤的發展。以上結果顯示CPT1C確實在類基底型乳癌細胞的高度上皮-間質細胞轉型及癌幹性中扮演不可或缺的角色，未來我將繼續探討調控CPT1C的分子機制及利用動物實驗進行驗證。我們的研究不僅對於新穎療法的開發有很大的幫助，也釐清現行
生酮飲食療法用於類基底型乳癌的謬誤。關鍵詞: 脂肪酸氧化、CPT1C、類基底型乳癌、上皮-間質細胞轉型、腫瘤幹細胞特性
Deferring Development: Setting Aside Cells for Future Use in Development and Evolution
為了解決Epithelial cells 的問題，作者 這樣論述：
Cory Bishop, Associate Professor in the Department of Biology at St. Francis-Xavier University, Antigonish, NS, Canada, received his PhD in Evolutionary Developmental Biology from Simon Fraser University, where he studied cellular and molecular regulation by nitric oxide signaling of metamorphosis i
n Deuterostomes. Throughout that work, and into his postdoctoral years, he maintained an interest in comparative embryology, larval biology, and life cycle evolution, especially as it related to the capacity of larvae to defer metamorphosis in the face of suboptimal conditions. He and colleagues dev
eloped methods to inject oligonucleotides into sea urchin juvenile rudiments, thus providing a method to experimentally investigate later stages that form inside the larval body. As a member of the Centre for Biofouling Research at St. Francis-Xavier University, he has applied his interest in metamo
rphosis to developing antifouling strategies for invasive species and, more recently, has focused his attention on a symbiotic relationship between unicellular green algae and embryos of several amphibians.Brian K. Hall, University Research Professor Emeritus at Dalhousie University in Halifax, NS,
Canada, was trained in Australia as an experimental embryologist. His research concentrated on the differentiation of skeletal tissues, especially, how epithelial-mesenchymal signaling initiates osteogenesis and chondrogenesis through the formation of cellular condensations. These studies led him to
earlier stages of development and the origin and function of skeletogenic neural crest cells. Comparative studies using embryos from all five classes of vertebrates provided a strong evolutionary component to his research. These studies, along with analyses of the developmental basis of homology, p
layed significant roles in the establishing of evolutionary developmental biology. A Fellow of the Royal Society of Canada, Foreign Fellow of the American Academy of Arts and Science, and recipient of a Killam Prize, he was one of eight individuals awarded the first Kovalevsky Medals in 2001 to reco
gnize the most distinguished scientists of the twentieth century in comparative zoology and evolutionary embryology.
透過基於基因本體之整合性分析識別卵巢上皮性腫瘤發病機轉的失調基因功能體
為了解決Epithelial cells 的問題，作者蘇國銘 這樣論述：
上皮性卵巢癌（EOCs）在晚期或復發的婦科惡性腫瘤中常是致命的和頑固的，其中漿液性佔絕大多數而卵巢清亮細胞癌（OCCC）是僅次於漿液性上皮性卵巢癌的第二常見的上皮性卵巢癌。即便經過腫瘤減積手術後加上化學藥物治療後仍有不少的患者有著較差的預後或是復發，故整體而言，對於卵巢癌的治療仍是一個相當大的挑戰。此外，邊緣性卵巢腫瘤(BOT)，包括漿液性 BOT與黏液性BOT，是屬於介於良性與惡性之間的卵巢疾病，雖然大部分的預後不差但是也有與卵巢癌不同的組織病理學特性。本研究使用以基因本體(GO)為基礎加上機器學習輔助運算的綜合分析去探討卵巢清亮細胞癌以及漿液性卵巢腫瘤包含漿液性邊緣性卵巢腫瘤與漿液性卵巢
癌的GEO資料庫中失調的基因體、功能途徑，藉以去識別重要的差異表達基因(DEG)。首先在卵巢清亮細胞癌的整合性分析中，發現無論是早期抑或是晚期，與免疫功能相關尤其是活化補體系統的替代途徑的功能失調在腫瘤發生佔有相當重要的關聯性，而補體C3與補體C5也影響了疾病無惡化存活期(Progression-free survival, PFS)和整體存活率(Overall survival, OS)且免疫染色結果是有意義的。而在漿液性卵巢腫瘤的分析中發現，SRC基因和功能失調的芳烴受體(AHR)結合路徑(Binding pathway)確實影響PFS和OS，而且與上皮細胞間質轉化(Epithelial-
mesenchymal transition, EMT)相關的鋅指蛋白SNAI2在腫瘤發生過程中有重要角色，並顯示出從漿液性 BOT 到卵巢癌有著逐漸上升的影響趨勢。未來，標靶治療可以專注於這些有意義的生物標誌並結合精確監測，以提高治療效果和患者存活率。