Specification的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列包括價格和評價等資訊懶人包

Applied Time Series Analysis for the Social Sciences: Specification, Estimation, and Inference

為了解決Specification的問題，作者Baker, Regina 這樣論述：

探討CPT1C在類基底型乳癌中調控上皮-間質轉型及腫瘤幹細胞特性所扮演的角色

為了解決Specification的問題，作者王慶弘 這樣論述：

代謝途徑重整是腫瘤的重要特徵之一，腫瘤細胞可藉由調控自身的代謝偏好而有利其在代謝壓力的情況下存活，並維持高速增生。有研究更進一步指出乳癌細胞傾向於透過調控脂肪酸氧化代謝的效率限制酶CPT1C來增加脂肪酸氧化的活性，進而促進細胞增生，甚至維持腫瘤幹細胞特性及產生抗藥性。因此，本研究旨在釐清類基底型乳癌是否透過調節CPT1C影響細胞脂肪酸氧化代謝的活性，進而誘發上皮-間質細胞轉型及腫瘤幹細胞特性。我們的先導結果指出，透過TCGA數據資料庫分析，CPT1C表現量在類基底型乳癌患者中高於其他乳癌類型，並在具有淋巴結轉移或遠端轉移的患者中具有較高的表現量;而在類基底型乳癌患者中，擁有較高CPT1C表現

量的族群同時存活率也較差。此外，在類基底型乳癌患者中，相較於其他CPT1同功酶(CPT1A、CPT1B)， 唯有CPT1C的表現量和存活率呈現負相關。接著，正常類基底型人類乳腺上皮細胞中過度表現CPT1C會增加脂肪酸氧化代謝活性，同時也誘導上皮-間質細胞轉型、細胞遷移、侵襲，並且提升腫瘤幹細胞特性；反之，利用微小干擾RNA抑制類基底型乳癌細胞株的CPT1C表現則可降低腫瘤的發展。以上結果顯示CPT1C確實在類基底型乳癌細胞的高度上皮-間質細胞轉型及癌幹性中扮演不可或缺的角色，未來我將繼續探討調控CPT1C的分子機制及利用動物實驗進行驗證。我們的研究不僅對於新穎療法的開發有很大的幫助，也釐清現行

生酮飲食療法用於類基底型乳癌的謬誤。關鍵詞: 脂肪酸氧化、CPT1C、類基底型乳癌、上皮-間質細胞轉型、腫瘤幹細胞特性

Psychology GCSE for Edexcel: Revise and Supplement

為了解決Specification的問題，作者Abbas, Ali 這樣論述：

This accessible and interactive textbook covers all compulsory and optional topics on the GCSE Edexcel Psychology syllabus introduced in 2017, including development, memory, psychological problems, brain and neuropsychology, social influence and research methods. All topics are covered in depth,

enabling you to digest and retain the information necessary and be ready for your exams.Packed with ideas and techniques designed to help you cement your knowledge, the book includes a number of unique and helpful features, such as: Expert tips from an experienced senior examiner to clarify key poin

ts and help you avoid making common errorsNew and updated exam questions to aid practiceActive learning tasks, such as key definitions and word gapsDouble page spreads outlining the studies you need to know, and their strengths and weaknessesCoverage of the new compulsory mathematical element which

was brought into the specification in 2017Perfect for revising psychological concepts, theories and studies in relation to the three critical assessment objectives, Psychology GCSE for Edexcel 2nd Edition is an essential resource for anyone taking a psychology GCSE using the Edexcel specification.